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FASUS: presented results of a new scientific study

Stability is the key to probiotic effectiveness

More than a hundred different probiotic products are available on the Serbian market, and the probiotic strains they contain are often identical or very similar. This creates the impression that high‑quality and effective probiotics are easy to find.

However, although choosing a clinically proven strain is the foundation of any serious probiotic formulation, that alone is not enough. If, during the declared shelf life, the product no longer contains a sufficient number of live probiotic cultures, it cannot be effective—regardless of how well the strain has been researched.This is precisely why increasing attention is being paid to the stability and viability of probiotic strains—from the moment of production until the end of shelf life.

The key question is no longer only whether a probiotic strain is clinically proven, but whether it remains stable and effective at the moment of use.At the recently concluded Pharmaceutical Meetings (FASUS), the results of a new scientific study were presented, examining the impact of packaging on probiotic stability, with a special focus on the strain Saccharomyces boulardii.

The study showed that traditional packaging often cannot fully protect probiotic cultures from moisture, temperature, and light, leading to a significant decline in the number of live cells over time—even before the expiration date.In contrast, the use of modern technological solutions—alu‑alu blister packaging with added adsorbents and a nitrogenization process—ensures that the declared number of live probiotic cultures is preserved until the very last day of shelf life. This guarantees that the product’s effectiveness remains consistent throughout the entire period of use.

These findings are particularly important for pharmacists, who recommend probiotics in daily practice with the goal of genuinely helping patients. Differences between probiotics are not reflected only in strain selection or price, but also in whether the product remains stable and active at the moment the patient takes it.

The development of DOX Pharm probiotic products is based precisely on these principles—combining clinically proven probiotic strains with advanced technological solutions in production and packaging. The goal is to give pharmacists confidence that they are recommending a stable and effective product, and to ensure that patients receive a probiotic that provides the expected health support throughout the entire period of use.